meta-analysis

Palmitoylethanolamide (PEA) is a natural compound that your body produces in response to various forms of cellular damage. Its primary role is to promote homeostasis, which is the body's ability to maintain a stable and balanced internal environment for optimal functioning and overall wellness. 

Berberine is a bioactive compound found in many plants, including goldenseal, Oregon grape, and barberry. It has been recognized for its health benefits for centuries, with its earliest known therapeutic use dating back to A.D. 200.  Today, Berberine continues to be an exciting focus of health and wellness research, with many studies investigating its potential for maintaining metabolic health.

Hyaluronic acid (HLA) is a naturally occurring gel-like substance that the body produces. It is abundantly present in the skin, joints, and eyes, where its exceptional ability to attract and retain water plays a crucial role in maintaining tissue hydration and lubrication.

The possible advantages of using Niacin for heart health have been recognized for decades. Research dating back to 1955 revealed that high doses of Niacin could notably decrease cholesterol levels in humans.

Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance the activation of the body's own self-repair proteins, called sirtuins. When sirtuins are activated, the effect is delayed aging, which has been demonstrated in a wide spectrum of experimental models, including mammals.