Category Archives: Bone & Muscle

Collagen Supports Skin, Joint, and Gut Health

Many studies suggest that collagen supplementation may be an effective way to counteract the decline in collagen production.

Study Shows NR Injections Increase Muscle NAD+ in Mice, Oral Supplementation Does Not

NR injections boosted NAD+ levels in skeletal muscle and white adipose tissue.

A ~140% increase in muscle NAD+ was observed after 7 days of IV administration of NR. Oral administration failed to increase NAD+ levels compared to the control group (figure A).

NMN and Resveratrol Work Synergistically to boost NAD+ in Heart and Skeletal Muscle

A new study shows that the combination of NMN and Resveratrol works synergistically to increase NAD+ levels in both heart and skeletal muscle tissues in mice. Combination treatments shown to boost efficacy It is becoming more common to treat age-related diseases with anti-aging cocktails, including NAD+ or NMN to boost efficacy.  NMN has been shown […]

Resveratrol Prevents Skeletal Muscle Atrophy and Senescence

Resveratrol (RSV) is a natural polyphenolic compound with antioxidant, anti-inflammatory, and anti-senescence and antitumor effects.  A new study investigated the effects of resveratrol (RSV) on cigarette smoke (CS)-induced skeletal muscle atrophy and cellular senescence in mice.   Thirty-two male mice were randomly divided into four groups: the control group (N), the resveratrol group (RSV), the emphysema […]

Study Shows NMN Supplementation or CD38 Inhibition Restores Cardiovascular Function in Mice

CD38 Deficiency Alleviates Ang II-Induced Vascular Remodeling By Inhibiting Small Extracellular Vesicle-Mediated Vascular Smooth Muscle Cell Senescence In Mice (Lu Gan, June 2021) In this study, researchers investigated the impact of NMN supplementation and CD38 inhibition on the cardiovascular function in mice. Declining NAD+ levels are a major contributor to cardiovascular disease in mice. It […]