Author Archives: Rebecca Crews

NMN Transporters and eNAMPT: Key Regulators of NAD+ Balance in Aging

“With these exciting developments, the further reformulated version of the concept, the NAD World 3.0, is now proposed, featuring multi-layered feedback loops mediated by NMN and eNAMPT for mammalian aging and longevity control.”

Trigonelline Improves Healing and Reduces Damage After Spinal Cord Injury in Rats

“Trigonelline shows neuroprotective properties in SCI rats by reducing allodynia, hyperalgesia, and inflammation, stabilizing mitochondrial enzyme complexes, and modulating apoptotic and neurotrophic factors.”

Liposomal Resveratrol Outperforms Standard Resveratrol for Diabetic Kidney Damage in Rats

"Our results also demonstrate significant improvement in kidney function in diabetic rats treated with LR at both 20 mg/kg and 40 mg/kg, suggesting that the liposomal formulation enhances resveratrol’s absorption and bioavailability."

NMN Enhanced Mitochondrial Stress Response and Improved Cognition in an Alzheimer’s Mouse Model

“We combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by which NAD+-boosting agent nicotinamide mononucleotide (NMN) regulates MSR in AD models.”