As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story of why this occurs Buildup of Damaged DNA and Faltering Ability to Repair Damage In a ground-breaking study spanning 0 to 82 year olds, they […]
Tag Archives: healthspan
Two recent studies have found that inhibition of CD38 (with 78c or PCC1) increase NAD+ levels and result in significant increases in lifespan and healthspan in mice.
Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance the activation of the body’s own self-repair proteins, called sirtuins. When sirtuins are activated, the effect is delayed aging, which has been demonstrated in a wide spectrum of experimental models, including mammals.
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field of longevity research. In a recent video, titled “Dr David Sinclair – Defeating Ageing & Living Longer | Modern Wisdom Podcast 343” [The video has been made private by the uploader], Dr. Sinclair discusses the supplements he is currently […]
This study fed lactating mice Nicotinamide Riboside (NR) in chow for 21 days after birth of offspring to measure the effect on the health of their pups who did not receive any NR. After 21 days, the pups were removed from the mothers and fed normal chow. These improvements in health and behavior persisted for […]
Researchers use supplementation with NMN, NR and NAD⁺ to restore levels of NAD⁺ in mice, making them look and behave like they did when young and extending their lifespan.
Although they have similar effect in some organs, there may be differences in the effect they have in other tissues throughout the body.
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