Author Archives: David

New Human Trial Shows NMN Reduced Blood Vessel Stiffness and Significantly Decreased Diastolic Blood Pressure

A new human trial using 36 healthy middle-aged participants was recently published showing positive efficacy for NMN.  In this 12-week, randomized, double-blind, placebo-controlled, parallel-group clinical trial, it was shown that just 125mg of NMN twice per day reduced blood vessel stiffness and significantly decreased diastolic blood pressure in participants with elevated glucose levels. (1) NAD+ […]

The Power of Green Tea Extract: Unlocking Health and Longevity Benefits

Green Tea: A Brief Overview Green tea is a popular beverage that has been consumed for thousands of years, originating in China and spreading throughout the world. It is made from the leaves of Camellia sinensis, a species of plant native to Asia. Unlike black and oolong tea, which are made from fermented leaves, green […]

Resveratrol: A Review of Human Clinical Trials

  Resveratrol, a naturally occurring compound found in grapes, berries, and other plants, has been the subject of numerous studies for its potential health benefits. It is known for its antioxidant, anti-inflammatory, and cardiovascular properties. In recent years, many human clinical trials have been conducted to investigate the effects of resveratrol on human health, including […]

NMN Human Trial Shows Increased Endurance, NAD+ Blood Levels, and Benefits to Bioage

A new NMN human trial using 80 middle-aged healthy adults showed that NMN supplementation was both safe and well tolerated.  It also showed that NMN significantly raised NAD+ blood levels, increased endurance, and benefited bioage. Study set out to determine safety and efficacy of NMN supplementation in 4 groups NAD+ levels are known to decline […]

NMN and Resveratrol Work Synergistically to boost NAD+ in Heart and Skeletal Muscle

A new study shows that the combination of NMN and Resveratrol works synergistically to increase NAD+ levels in both heart and skeletal muscle tissues in mice. Combination treatments shown to boost efficacy It is becoming more common to treat age-related diseases with anti-aging cocktails, including NAD+ or NMN to boost efficacy.  NMN has been shown […]

Intravenous NMN Results in Massive Decrease in Blood Triglyceride Levels

Previous human clinical trials have shown that NAD+ levels can be safely and efficiently replenished by oral NMN supplementation. Until a recent study, however, the safety and efficacy of intravenous NMN had not been firmly established. Intravenous NMN shown to be safe and effective Using 10 healthy volunteers, results indicated that intravenous NMN is both […]

NR Shows Ability to Promote DNA Repair and Increase Lifespan by 25% in Mice

The ability to repair DNA damage decreases over time, causing an accumulation of mutations that can affect cellular function, viability, and an increase in the aging process.  In a new study, mice engineered to age quickly were tested to see which compounds were best at promoting DNA repair. Nicotinamide Riboside (NR) shown to increase lifespan […]

Exercise Increases Blood Vessel Growth, Density, and Benefits Aging Muscle

New studies are showing the benefits of exercise on blood vessel growth and aging muscle.  The loss of muscle tissue, called sarcopenia, is a natural part of the aging process.  These new studies show that steady exercise can help to overcome the loss of muscle tissue well into later years. Loss of muscle tissue starts […]

NAD+ Reduces Mutations and Incidence of Skin Cancer

In a new study by Brown University School of Medicine, it was shown that oral nicotinamide (NAM) supplementation decreased the incidence of keratinocyte carcinoma (KC) in high-risk skin cancer patients.  NAM is converted to NAD+ in the body and it is NAD+ that is believed to be responsible for for the decrease in Keratinocyte carcinoma […]

Resveratrol Prevents Skeletal Muscle Atrophy and Senescence

Resveratrol (RSV) is a natural polyphenolic compound with antioxidant, anti-inflammatory, and anti-senescence and antitumor effects.  A new study investigated the effects of resveratrol (RSV) on cigarette smoke (CS)-induced skeletal muscle atrophy and cellular senescence in mice.   Thirty-two male mice were randomly divided into four groups: the control group (N), the resveratrol group (RSV), the emphysema […]

Fisetin Effectively Eliminates Senescent Cells and Restores Stem Cells

Fisetin is a flavonoid found in fruits and vegetables and has been shown to have powerful senolytic properties.  In a new study, fisetin was shown to prevent immune cells from becoming senescent, allowing them to enter into a state of apoptosis or cellular suicide, a normal process at the end of a cell’s life cycle. […]

NMN restores kidney function and prevents kidney damage

Use of NMN supplements was shown to activate Sirtuin-1, one of the body’s self repair enzymes, to repair kidney damage and restore kidney function in mice. (1) Kidney damage accumulates with age As we age, we accumulate kidney scarring and tissue hardening, which can impede the kidneys ability to filter proteins in the blood and […]