“We combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by which NAD+-boosting agent nicotinamide mononucleotide (NMN) regulates MSR in AD models.”
Category Archives: Research
“NAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and degradation, supporting the rationale for NAD+ augmentation to attenuate disease severity.”
“NMN supplementation could improve the health status of aging ovaries and enhance ovarian reserve, offering new insights into addressing fertility challenges in older women through assisted reproductive technology.”
Collectively, these preliminary findings support the effectiveness of daily liposomal GSH administration at elevating stores of GSH and impacting immune function and levels of oxidative stress.
This meta-review found that NMN improves muscle function, reduces insulin resistance, and lowers liver enzyme levels in middle-aged and elderly participants. Summary This meta-analysis of 9 randomized controlled trials with 412 participants evaluated the effects of NMN on muscle and liver function in middle-aged and elderly individuals. The study found that NMN significantly improved muscle […]
This study examined the effects of long-term NMN supplementation on lifespan, healthspan, and metabolic health in male and female mice. Effects of NMN on Lifespan and Healthspan in Aging Mice Mice were divided into two main groups based on sex and treatment: NMN group: Received NMN in drinking water (~550 mg/kg/day). Control group: Received regular […]
Green Tea Extract, in its concentrated form, has shown significant potential in addressing age-related concerns related to heart health, cognitive function, and metabolism.
This research reviews the current evidence on NMN metabolism and compares the effects of different administration routes.
“In comparison to NAD+ IV, NR IV was infused faster, and the infusion experience was more tolerable.”