Category Archives: Research

Health Conditions Linked to NAD+ Decline

Many diseases and biological stressors disrupt NAD+ metabolism and are associated with low levels of NAD+, such as obesity, infection, alcohol consumption, and high blood pressure.

NR Regulates the Cardiac Internal Clock of Aged Mice

Circadian rhythm is your body’s internal clock that permits anticipation of daily patterns, regulating when it’s time to sleep, wake up, eat, and digest. This study evaluated the effects of NR supplementation on age-related changes in the heart’s circadian rhythm.

Novel Delivery System Improves NMN Absorption in Mice

“Upon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN, leading to elevated plasma levels of both NAD+ and its precursor, NR.”

Evidence for the Health Effects of Hesperidin

Hesperidin is a flavonoid, a type of plant compound that has been shown to have a wide range of health benefits. It is found primarily in citrus fruits, such as oranges, lemons, grapefruit, and limes. Hesperidin exhibits anti-inflammatory and antioxidant activity, protecting cells from two key contributors to the onset of age-related and chronic diseases: inflammation and oxidative stress.