A recent study investigated the effects of NMN and NR on ovary health and function in middle-aged rats. “This study reveals that NMN alone or NR alone can rebalance mitochondrial dynamics by decreasing excessive fission in middle-aged rat ovaries, thus alleviating mitochondrial stress and correcting aging-induced folliculogenesis abnormalities.” This graph shows the number of healthy […]
Category Archives: Research
Creatine is an amino acid derivative stored in your muscles and used to create energy for movement. Every cell in the body relies on Adenosine Triphosphate (ATP) as a source of energy that through muscle contraction, uses ATP and releases Adenosine Diphosphate (ADP). Stores of Creatine in your muscles help to quickly turn ADP back to ATP for additional energy.
This preprint investigated the neuroprotective effects of berberine pretreatment in a rat model of Parkinson’s disease.
Glycine is a non-essential amino acid that is nonetheless necessary for many health-promoting metabolic processes. It is an integral part of protiens made inside the body, a precursor for important biomolecules like glutathione and creatine, and acts as an inhibitory (calming) neurotransmitter in the central nervous system. Research strongly supports glycine’s potential to protect health […]
This study investigated the potential of NMN-loaded nanoparticles to prevent age-related decline in a model of aging mice.
“Our results add trigonelline to the list of established dietary NAD+ boosters.”
A new study found injection of NAD+ using a novel liposome-like nano-particle carrier reduced overgrowth of smooth muscle cells and improved blood vessel healing in rats with narrowed arteries.
"Liposome-based NR loading is an effective strategy for improving the pharmacokinetics and bioavailability of NR, especially to the brain."
While all three precursors – Niacin, NR, and NMN – elevate NAD+ levels, their journeys within the body are distinct. Understanding these individual pathways is crucial, as they may have significant effects on outcomes beyond just the NAD+ level itself.
“We showed that NMN consistently extended the healthy and median lifespan of Zmpste24-/- and improved the Zmpste24-/- ageing phenotype."
"Compared to traditional routes, the nasal administration of drugs can direct the rapid CNS absorption to brain tissues, thereby circumventing the hepatic first-pass metabolism and gastric degradation and allowing fast onset of pharmacological action."