A new study shows that the combination of NMN and Resveratrol works synergistically to increase NAD+ levels in both heart and skeletal muscle tissues in mice. Combination treatments shown to boost efficacy It is becoming more common to treat age-related diseases with anti-aging cocktails, including NAD+ or NMN to boost efficacy. NMN has been shown […]
Category Archives: Research
Previous human clinical trials have shown that NAD+ levels can be safely and efficiently replenished by oral NMN supplementation. Until a recent study, however, the safety and efficacy of intravenous NMN had not been firmly established. Intravenous NMN shown to be safe and effective Using 10 healthy volunteers, results indicated that intravenous NMN is both […]
The ability to repair DNA damage decreases over time, causing an accumulation of mutations that can affect cellular function, viability, and an increase in the aging process. In a new study, mice engineered to age quickly were tested to see which compounds were best at promoting DNA repair. Nicotinamide Riboside (NR) shown to increase lifespan […]
New Research Shows Resveratrol Can Help Prevent Muscle Loss & Senescence in Mice Resveratrol is a heavily studied anti-aging polyphenol packed with health benefits. To date, the compound has been shown to have antioxidant, anti-inflammatory, and anti-senescence effects. A recent study has shown that Resveratrol can prevent muscle atrophy and senescence in mice. The study […]
In a new study by Brown University School of Medicine, it was shown that oral nicotinamide (NAM) supplementation decreased the incidence of keratinocyte carcinoma (KC) in high-risk skin cancer patients. NAM is converted to NAD+ in the body and it is NAD+ that is believed to be responsible for for the decrease in Keratinocyte carcinoma […]
Shilajit is a tar-like sticky black substance found mainly in mountainous regions. It is primarily found in the Himalayas and is vastly popular in South Asia. Shilajit has a range of benefits associated with it. It is quite famous for its boosting effects on male sexual wellness and fertility. You can see the dark color […]
Resveratrol (RSV) is a natural polyphenolic compound with antioxidant, anti-inflammatory, and anti-senescence and antitumor effects. A new study investigated the effects of resveratrol (RSV) on cigarette smoke (CS)-induced skeletal muscle atrophy and cellular senescence in mice. Thirty-two male mice were randomly divided into four groups: the control group (N), the resveratrol group (RSV), the emphysema […]
A new study shows that increased levels in the brain of a molecule called Slc128a, which transports NMN into cells, reduces a type of muscle decline in older adults called sarcopenia. Likewise, they showed that reducing levels of Slc128a in the brain caused the muscles to become fatigued and weakened again. Doubling Slc128a Dramatically Improved […]
As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story of why this occurs Buildup of Damaged DNA and Faltering Ability to Repair Damage In a ground-breaking study spanning 0 to 82 year olds, they […]
Intercellular communication: communication between cells All species of animals, including the human being, are multicellular organisms (an organism that consists of more than one cell). In order to work collectively and maintain the homeostasis across multiple tissues, our cells have developed multiple different ways to receive, process, and transmit information between each other, including endocrine, […]
Two recent studies have found that inhibition of CD38 (with 78c or PCC1) increase NAD+ levels and result in significant increases in lifespan and healthspan in mice.
Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance the activation of the body’s own self-repair proteins, called sirtuins. When sirtuins are activated, the effect is delayed aging, which has been demonstrated in a wide spectrum of experimental models, including mammals.