Category Archives: Metabolic Health

Coenzyme Q10 in Aging, Heart Health, and Fertility

CoQ10 may extend its potential benefits beyond its traditional role in energy production. Emerging research suggests it could provide cardioprotective effects and reduce migraine symptoms. Moreover, its anti-inflammatory and antioxidant properties have shown promise in addressing age-related disorders and various diseases.

Study Shows NMN Protects Against Lung Damage in Mice

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure and protected against pulmonary fibrosis in mice.

The Comprehensive Effects of Berberine for Metabolic Health

Berberine is a bioactive compound found in many plants, including goldenseal, Oregon grape, and barberry. It has been recognized for its health benefits for centuries, with its earliest known therapeutic use dating back to A.D. 200.  Today, Berberine continues to be an exciting focus of health and wellness research, with many studies investigating its potential for maintaining metabolic health.

Palmitoylethanolamide (PEA) in Pain Relief, Gut Health, and Neuroprotection

Palmitoylethanolamide (PEA) is a natural compound that your body produces in response to various forms of cellular damage. Its primary role is to promote homeostasis, which is the body’s ability to maintain a stable and balanced internal environment for optimal functioning and overall wellness. 

Therapeutic Potential of Quercetin in Allergy Management and Inflammation

Quercetin, a bioactive compound found in various fruits and vegetables, has attracted significant attention for its potential therapeutic effects against allergies. 

Study Finds Berberine Improves Obesity, Glucose, Lipids, & Liver Health in Mice

“Recent studies showed that BBR significantly reduced liver steatosis, improved insulin resistance, alleviated glucose and lipid metabolism disorders, and exhibited therapeutic effects on NAFLD in humans and mice.”

Nicotinamide Mononucleotide (NMN) Increases Plasma NMN and Insulin Levels in Healthy Subjects

This new study found that for the first time that NMN supplementation in humans increases levels of NMN in blood plasma.

All previous studies with NMN and NR have not been able to detect measurable increase in blood levels of NMN or NR.

They also found increased levels of NAD+ and insulin levels.

NMN lowers Cholesterol, bodyweight, and blood pressure in 28 day trial with overweight older adults

A regimen of 1000 mg of MIB-626 twice daily was safe and efficacious

MIB-626 treatment was associated with a substantial increase in blood NAD level from baseline to days 14 and 28

Circulating NMN levels did not change significantly in either group…

Newly Found Benefits of Resveratrol in Health and Anti-aging

Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance the activation of the body’s own self-repair proteins, called sirtuins. When sirtuins are activated, the effect is delayed aging, which has been demonstrated in a wide spectrum of experimental models, including mammals.

NAD+ and the Hallmarks of Aging Series – Part 6: Mitochondrial Dysfunction

Mitochondria – More than Powerplants in Cells Mitochondria are the large organelles that exist in most human cells. They are the critical organelles that generate ATP through the respiratory chain and produce the intermediate metabolites that are essential to various cellular processes.  During aging, the respiratory chain losses its efficacy and the membrane of the […]

How NAD+ Boosts ATP and What it Means for Health and Aging

Much of the attention on the benefits of restoring NAD+ levels focus on its role in activating sirtuins. However, scientific research shows that NAD supplementation has a clear beneficial effect not only on ageing itself but also on a vast range of age-related disorders through improving the levels of ATP. Declining ATP as we age […]

1st NMN Human Study Demonstrates Safety and Faster Utilization than NR

The single oral administration of NMN was safe and effectively metabolized in healthy men without causing any significant deleterious effects. Thus, the oral administration of NMN was found to be feasible, implicating a potentialtherapeutic strategy to mitigate aging-related disorders in humans.