NMN & NAD+ PRECURSORS

NMN Enhanced Mitochondrial Stress Response and Improved Cognition in an Alzheimer’s Mouse Model

“We combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway [...]

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04
Nov
Increased NAD+ Turnover, Minor Decline in Levels in COVID-19 Patients

“NAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and [...]

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15
Oct
NMN Improved Aging Parameters in Clinical Trial

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11
Oct
NMN Offers More Protection Than NR in Friedreich’s Ataxia Mice

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30
Aug
Long Term NMN Use Extends Lifespan and Healthspan in Mice with Sex-Specific Effects

This study examined the effects of long-term NMN supplementation on lifespan, healthspan, and metabolic health [...]

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22
Aug
NMN Enhances Cellular Protection and Cognitive Function in Alzheimer’s Disease Mice

[...]

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20
Aug

LATEST ARTICLES

Aging & Longevity, Longevity Supplements, NAD+, NMN, Research

NMN Improves Blood Pressure in Humans with Hypertension

Posted on by Rebecca Crews

“Overall, the present study may shed new light on novel strategies in which NAD+ boosting therapy, including NMN supplement and CD38 inhibition, may turn out to be a promising therapeutic measure to treat patients with hypertension.”

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Aging & Longevity, Longevity Supplements, Metabolic Health, Research

The Science Behind 5-Hydroxytryptophan (5-HTP)

Posted on by Rebecca Crews

5-hydroxytryptophan (5-HTP) is a natural substance that the body makes to produce serotonin, a neurotransmitter that helps regulate mood, sleep, appetite, and pain.

Supplementation with 5-HTP has shown to increase levels of serotonin in the body, which has potential benefits for a number of conditions.

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

Study Shows NR Improves Glucose, Lipids, And Body Composition in Mice On A High-Fat Diet

Posted on by Rebecca Crews

This study showed that NR supplementation protected mice from HFD-induced metabolic dysfunction, specifically through protecting mitochondrial function in the skeletal muscle. 

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Aging & Longevity, Immune System, Longevity Supplements, Metabolic Health, Research

Apigenin Balances the Gut Microbiome and Improves Ulcerative Colitis in Mice

Posted on by Rebecca Crews

This study examined the effects of Apigenin on inflammation, gut barrier integrity, and the gut microbiome in mice with ulcerative colitis (UC). 

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

The Role of Resveratrol in Healthy Aging and Metabolism

Posted on by Rebecca Crews

More than  240 clinical trials have been conducted to understand the potential health effects of Resveratrol. Evidence suggests Resveratrol may enhance longevity, heart health, glucose and fat metabolism, and bone health.

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Aging & Longevity, Longevity Supplements, NAD+, NMN, Research

Study Reveals New Technique to Quickly and Accurately Measure Blood NAD+ Levels

Posted on by Rebecca Crews

This study revealed a new technique to quickly, accurately, and inexpensively test blood NAD+ levels in humans to allow repeated testing throughout the day in clinical settings, and eventually at home.
Using this method, they were able to identify 6 different combinations of molecules that can be used to “reset” the age of cells to a youthful, healthy state.

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Aging & Longevity, Immune System, Longevity Supplements, Metabolic Health, Research

Palmitoylethanolamide (P.E.A.) Reduces Inflammation and Anxiety in Obese Mice

Posted on by Rebecca Crews

This study showed that P.E.A. protected mice from HFD-induced anxiety-like behavior and inflammation. “As our data demonstrated, the blunted synthesis of pro-inflammatory cytokines by PEA can stop this vicious cycle among brain immune cells, limiting the progression of enduring neuroinflammation.”

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

Coenzyme Q10 and Migraine Relief

Posted on by Rebecca Crews

A clinical trial examined Coenzyme Q10’s (CoQ10’s) effects on episodic migraines in women, finding significant reductions in migraine frequency, duration, severity. CoQ10 also reduced the levels of TNF-ɑ and CGRP, a peptide linked to migraines that promotes inflammation and pain signaling. 

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

Anti-Aging Effects of NMN – Human Clinical Trials Review

Posted on by Ben Johnson

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

Study Shows Resveratrol Preserves Muscle Health in Aged Mice

Posted on by Rebecca Crews

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

Coenzyme Q10 in Aging, Heart Health, and Fertility

Posted on by Rebecca Crews

CoQ10 may extend its potential benefits beyond its traditional role in energy production. Emerging research suggests it could provide cardioprotective effects and reduce migraine symptoms. Moreover, its anti-inflammatory and antioxidant properties have shown promise in addressing age-related disorders and various diseases.

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

Study Shows NMN Protects Against Lung Damage in Mice

Posted on by Rebecca Crews

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure and protected against pulmonary fibrosis in mice.

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