NMN & NAD+ PRECURSORS

NMN Transporters and eNAMPT: Key Regulators of NAD+ Balance in Aging

“With these exciting developments, the further reformulated version of the concept, the NAD World 3.0, [...]

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05
Feb
NMN Rejuvenates Skin in Aging Mice

NMN treatment effectively revitalized aging skin in mice, enhancing both its visible appearance and underlying [...]

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16
Jan
A Novel NAD+ Precursor (NRH) Improves Glucose and Fat Metabolism in Obese Mice

“To our knowledge, this is the first report showing that NRH can reach multiple tissues [...]

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01
Jan
NMN Protects Mitochondria and Reduces Heart Injury in Septic Mice

This study demonstrated that NMN protected heart function in septic mice by reducing mitochondrial free [...]

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09
Dec
NMN Enhanced Mitochondrial Stress Response and Improved Cognition in an Alzheimer’s Mouse Model

“We combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway [...]

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04
Nov
Increased NAD+ Turnover, Minor Decline in Levels in COVID-19 Patients

“NAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and [...]

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15
Oct

LATEST ARTICLES

Immune System, Kidney, Liver & Lungs, Lifestyle, Diet & Fitness, NAD+, Neurological, Research

Health Conditions Linked to NAD+ Decline

Posted on by Rebecca Crews

Many diseases and biological stressors disrupt NAD+ metabolism and are associated with low levels of NAD+, such as obesity, infection, alcohol consumption, and high blood pressure.

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Aging & Longevity, NAD+, NR, Research

NR Regulates the Cardiac Internal Clock of Aged Mice

Posted on by Rebecca Crews

Circadian rhythm is your body’s internal clock that permits anticipation of daily patterns, regulating when it’s time to sleep, wake up, eat, and digest. This study evaluated the effects of NR supplementation on age-related changes in the heart’s circadian rhythm.

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Aging & Longevity, Longevity Supplements, NAD+, NMN, Research

Novel Delivery System Improves NMN Absorption in Mice

Posted on by Rebecca Crews

“Upon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN, leading to elevated plasma levels of both NAD+ and its precursor, NR.”

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

Evidence for the Health Effects of Hesperidin

Posted on by Rebecca Crews

Hesperidin is a flavonoid, a type of plant compound that has been shown to have a wide range of health benefits. It is found primarily in citrus fruits, such as oranges, lemons, grapefruit, and limes. Hesperidin exhibits anti-inflammatory and antioxidant activity, protecting cells from two key contributors to the onset of age-related and chronic diseases: inflammation and oxidative stress.

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

Research-Backed Benefits of Ashwagandha

Posted on by Rebecca Crews

Modern research supports the traditional uses of Ashwaganda, showing it may help reduce stress, anxiety, fatigue, improve cognitive function, boost the immune system, and help manage blood sugar levels.

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Aging & Longevity, Longevity Supplements, NAD+, NMN, Research

NMN Reduces Heart Failure and Extends Lifespan in Mice

Posted on by Rebecca Crews

“These results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32 cardiomyocyte–specific knockout mice, thereby prolonging their lifespan.”

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Aging & Longevity, Immune System, Kidney, Liver & Lungs, Longevity Supplements, Metabolic Health, NAD+, NMN, Research

Quercetin Prevents Bone Loss and Preserves Cartilage in Rats

Posted on by Rebecca Crews

This study showed that Quercetin protected rats with osteoarthritis against bone and cartilage damage by reducing inflammation and modulating levels of proteins associated with cartilage health.

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Aging & Longevity, Longevity Supplements, NAD+, NMN, Research

NMN Improves Blood Pressure in Humans with Hypertension

Posted on by Rebecca Crews

“Overall, the present study may shed new light on novel strategies in which NAD+ boosting therapy, including NMN supplement and CD38 inhibition, may turn out to be a promising therapeutic measure to treat patients with hypertension.”

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