NMN & NAD+ PRECURSORS

Long Term NMN Use Extends Lifespan and Healthspan in Mice with Sex-Specific Effects

This study examined the effects of long-term NMN supplementation on lifespan, healthspan, and metabolic health [...]

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NMN Administration Route Impacts Metabolism and Efficacy

This research reviews the current evidence on NMN metabolism and compares the effects of different [...]

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NR IV Exhibits Faster NAD+ Rise and Better Tolerability in Humans

“In comparison to NAD+ IV, NR IV was infused faster, and the infusion experience was [...]

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Large Variation Between Individuals in Response to NMN Supplementation

“Because of the high interindividual variability of the NADΔ after NMN supplementation, monitoring NAD concentration [...]

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LATEST ARTICLES

Study Reveals New Technique to Quickly and Accurately Measure Blood NAD+ Levels

This study revealed a new technique to quickly, accurately, and inexpensively test blood NAD+ levels in humans to allow repeated testing throughout the day in clinical settings, and eventually at home.
Using this method, they were able to identify 6 different combinations of molecules that can be used to “reset” the age of cells to a youthful, healthy state.

Palmitoylethanolamide (P.E.A.) Reduces Inflammation and Anxiety in Obese Mice

This study showed that P.E.A. protected mice from HFD-induced anxiety-like behavior and inflammation. “As our data demonstrated, the blunted synthesis of pro-inflammatory cytokines by PEA can stop this vicious cycle among brain immune cells, limiting the progression of enduring neuroinflammation.”

Coenzyme Q10 and Migraine Relief

A clinical trial examined Coenzyme Q10’s (CoQ10’s) effects on episodic migraines in women, finding significant reductions in migraine frequency, duration, severity. CoQ10 also reduced the levels of TNF-ɑ and CGRP, a peptide linked to migraines that promotes inflammation and pain signaling. 

Anti-Aging Effects of NMN – Human Clinical Trials Review

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

Study Shows Resveratrol Preserves Muscle Health in Aged Mice

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

Coenzyme Q10 in Aging, Heart Health, and Fertility

CoQ10 may extend its potential benefits beyond its traditional role in energy production. Emerging research suggests it could provide cardioprotective effects and reduce migraine symptoms. Moreover, its anti-inflammatory and antioxidant properties have shown promise in addressing age-related disorders and various diseases.

Study Shows NMN Protects Against Lung Damage in Mice

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure and protected against pulmonary fibrosis in mice.

Study Finds Liposomal Berberine Improves Glucose, Lipids, and Inflammation in Rats

“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited remarkable protective effects against hepatic tissue damage, steatosis, inflammation, insulin resistance, and hepatocellular enzyme imbalance.”

Study Demonstrates Age Reversal through Cellular Reprogramming with Chemical Cocktails – David Sinclair

A team of scientists from Harvard Medical School discovered a method to distinguish young cells from old and senescent cells in real time.  This allowed them to quickly screen the effect of different molecules on cellular health.

Using this method, they were able to identify 6 different combinations of molecules that can be used to “reset” the age of cells to a youthful, healthy state.

The Comprehensive Effects of Berberine for Metabolic Health

Berberine is a bioactive compound found in many plants, including goldenseal, Oregon grape, and barberry. It has been recognized for its health benefits for centuries, with its earliest known therapeutic use dating back to A.D. 200.  Today, Berberine continues to be an exciting focus of health and wellness research, with many studies investigating its potential for maintaining metabolic health.

Palmitoylethanolamide (PEA) in Pain Relief, Gut Health, and Neuroprotection

Palmitoylethanolamide (PEA) is a natural compound that your body produces in response to various forms of cellular damage. Its primary role is to promote homeostasis, which is the body’s ability to maintain a stable and balanced internal environment for optimal functioning and overall wellness. 

Therapeutic Potential of Quercetin in Allergy Management and Inflammation

Quercetin, a bioactive compound found in various fruits and vegetables, has attracted significant attention for its potential therapeutic effects against allergies.