Category Archives: Aging & Longevity

NR Regulates the Cardiac Internal Clock of Aged Mice

Circadian rhythm is your body’s internal clock that permits anticipation of daily patterns, regulating when it’s time to sleep, wake up, eat, and digest. This study evaluated the effects of NR supplementation on age-related changes in the heart’s circadian rhythm.

Novel Delivery System Improves NMN Absorption in Mice

“Upon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN, leading to elevated plasma levels of both NAD+ and its precursor, NR.”

Evidence for the Health Effects of Hesperidin

Hesperidin is a flavonoid, a type of plant compound that has been shown to have a wide range of health benefits. It is found primarily in citrus fruits, such as oranges, lemons, grapefruit, and limes. Hesperidin exhibits anti-inflammatory and antioxidant activity, protecting cells from two key contributors to the onset of age-related and chronic diseases: inflammation and oxidative stress.

Research-Backed Benefits of Ashwagandha

Modern research supports the traditional uses of Ashwaganda, showing it may help reduce stress, anxiety, fatigue, improve cognitive function, boost the immune system, and help manage blood sugar levels.

NMN Reduces Heart Failure and Extends Lifespan in Mice

“These results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32 cardiomyocyte–specific knockout mice, thereby prolonging their lifespan.”

Quercetin Prevents Bone Loss and Preserves Cartilage in Rats

This study showed that Quercetin protected rats with osteoarthritis against bone and cartilage damage by reducing inflammation and modulating levels of proteins associated with cartilage health.

NMN Improves Blood Pressure in Humans with Hypertension

“Overall, the present study may shed new light on novel strategies in which NAD+ boosting therapy, including NMN supplement and CD38 inhibition, may turn out to be a promising therapeutic measure to treat patients with hypertension.”