Category Archives: Aging & Longevity

Study Shows NMN Protects Against Lung Damage in Mice

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure and protected against pulmonary fibrosis in mice.

Study Finds Liposomal Berberine Improves Glucose, Lipids, and Inflammation in Rats

“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited remarkable protective effects against hepatic tissue damage, steatosis, inflammation, insulin resistance, and hepatocellular enzyme imbalance.”

The Comprehensive Effects of Berberine for Metabolic Health

Berberine is a bioactive compound found in many plants, including goldenseal, Oregon grape, and barberry. It has been recognized for its health benefits for centuries, with its earliest known therapeutic use dating back to A.D. 200.  Today, Berberine continues to be an exciting focus of health and wellness research, with many studies investigating its potential for maintaining metabolic health.

Palmitoylethanolamide (PEA) in Pain Relief, Gut Health, and Neuroprotection

Palmitoylethanolamide (PEA) is a natural compound that your body produces in response to various forms of cellular damage. Its primary role is to promote homeostasis, which is the body’s ability to maintain a stable and balanced internal environment for optimal functioning and overall wellness. 

Therapeutic Potential of Quercetin in Allergy Management and Inflammation

Quercetin, a bioactive compound found in various fruits and vegetables, has attracted significant attention for its potential therapeutic effects against allergies. 

Study Shows NR Injections Increase Muscle NAD+ in Mice, Oral Supplementation Does Not

NR injections boosted NAD+ levels in skeletal muscle and white adipose tissue.

A ~140% increase in muscle NAD+ was observed after 7 days of IV administration of NR. Oral administration failed to increase NAD+ levels compared to the control group (figure A).

NMN lowers Cholesterol, bodyweight, and blood pressure in 28 day trial with overweight older adults

A regimen of 1000 mg of MIB-626 twice daily was safe and efficacious

MIB-626 treatment was associated with a substantial increase in blood NAD level from baseline to days 14 and 28

Circulating NMN levels did not change significantly in either group…

Major Research Studies Show Lifespan Extension from Green Tea

Reduction in All-Cause Mortality Correlates with Green Tea Consumption.

Numerous large-scale studies with over 300,000+ participants have demonstrated that green tea consumption is associated with a significant decrease in all-cause mortality.

Studies of this length and magnitude are rare. 

The Power of Green Tea Extract: Unlocking Health and Longevity Benefits

Green Tea: A Brief Overview Green tea is a popular beverage that has been consumed for thousands of years, originating in China and spreading throughout the world. It is made from the leaves of Camellia sinensis, a species of plant native to Asia. Unlike black and oolong tea, which are made from fermented leaves, green […]

Does NR Cause Cancer? Response to A Recent Article

  A recent article in sciencedaily.com took some research out of context and wrote a review with a click-bait title that caused a lot of uproar as others repeated the faulty review. Here is the title of the original research: “A bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link […]

New Research with NMN by IV Shows Much Stronger Effect Than Oral Supplementation

There are now 12 studies published to date in humans with NMN supplementation. The previous 11 studies used oral delivery of NMN capsules, and were generally quite positive. This most recent study used a single dose of NMN by IV. Researchers were surprised to find a 75% drop in triglycerides. There haven’t been any previous […]